ExCellerate™
Animal-Component Free NK Media
Accelerate Your Development of NK Cell Therapies
Natural Killer (NK) cells play an essential role in adaptive and innate immune responses, and due to their intrinsic and non-specific anti-tumor activity, human NK cells have been employed as anti-cancer therapies. Robust expansion and maintenance of NK Cells are critical to facilitate NK cell therapy.
ExCellerate Human NK Cell Expansion Media is animal-component free (RUO) available in 1L bottles. Development of the biosimilar GMP Media in bags and bottles is in production.
Exceptional Expansion; Feeder & Feeder-Free
- Supports feeder- and serum-free expansion of NK cells
- Phenol red-free formulation
- Animal component-free media to support patient safety
- Supports NK cell expansion from PBMCs or purified CD3+-depleted PBMCs
- Protocol to support G-Rex feeder-cell culture process
ExCellerate media support expansion and growth of gene-edited NK cells with TcBuster
Across a sampling of donors, it can be seen that non-viral TcBuster gene-edited NK cells show comparative fold expansion and growth against non-edited. Cumulative expansion outperforms non-edited cells in most cases. CAR expression also yields high quality and quantity when pairing TcBuster with ExCellerate NK Media.
Why Choose ExCellerate NK Media?
Serum-Free Culture with Feeder-Based Platform
Versatile NK Cell Expansion Media
ExCellerate Human NK Cell Expansion Media is optimized for NK cell expansion when used in combination with Recombinant Human Cytokines from Bio-Techne R&D Systems; however, this versatile media also provides robust growth using a variety of cytokine combinations (IL-2, IL-15, IL-12, IL-18, and IL-21) and cell activation methods, including particle, bead-based, or plate-bound Human NKp46/NCR1 Antibody.
The media supports both feeder-based and feeder-free expansion methods.
How to order
NK Media Sample Request form
Additional Resources
Determining Optimal Seeding Density for Human T Cell Expansion in G-Rex
G-Rex Closed-system Bioreactors
- G-Rex Bioreactor mechanism of action
- Benefits for cell therapy manufacturing
- GatheRex Cell Harvest Pump
- User testimonials
ScaleReady Portfolio Overview
- Portfolio introduction
- G-Rex Bioreactors and raw materials
- Cell processing instruments